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Thread: Bardoxolone methyl

  1. #1
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    Bardoxolone methyl

    Bardoxolone methyl (also known as “RTA 402” and “CDDO-methyl ester”) is an orally-available first-in-class synthetic triterpenoid belonging to the antioxidant inflammation modulator (AIM) class. It is the most potent known inducer of the Nrf2 pathway to enter clinical development and works to suppress both oxidative stress and inflammation.

    A Nrf2 activator that inhibits proliferation and induces differentiation and apoptosis in various cancer cells; Antioxidant inflammation modulator (AIM); For the treatment of advanced chronic kidney disease (CKD) in type 2 diabetes mellitus patients.
    Last edited by sherrycd; 10-18-2016 at 11:17 PM.

  2. #2
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    Hi
    Can u recommend a book, that might enable me to understand your posts.
    I know something about most things, but nothing on your subject. Where would u suggest starting.

  3. #3
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    Organic chemistry basics will be a good starter. After reading such books, you can have a general idea about how such substance as drugs play in body to fight against diseases.

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